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The discretely higher Rotterdam CT AUC value was not statistically significant when compared to the Helsinki CT, and p values for the comparison are presented in Supplementary Table S1. Receiver operating characteristic curves for prediction of (A) 14-day mortality and (B) in-hospital mortality. Lastly, like the other temporal properties, the sampling frequency also varies across the datasets. The remaining datasets have constant sampling frequency within the dataset, with the highest sampling frequency of 512 Hz in Siena Scalp EEG and the lowest in the University of Bonn at 173.6 Hz. Sampling frequency of the datasets can also be found in Table 8.

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Future work could include performing a more detailed survey of how studies make use of the data. Specifically, what properties of the data do studies depend on, what other assumptions do they make about datasets (e.g., assume a balanced dataset), and what techniques they used to overcome some of the issues of the dataset. Lastly, there are huge variations across several characteristics that prevent studies from truly testing their trained algorithm on another dataset without re‐tuning the algorithm. The diversity of the channels used varied across the datasets as shown in Table 2. Both the University of Bonn and Hauz Khas datasets have only one channel that was cut and selected from continuous EEG recordings from multiple patients to form a single channel that consists of EEG segments from multiple channels. The number of channels in the Siena Scalp EEG dataset is 29, with the exception of one subject who has a 20‐channel EEG recording.

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• The Kaggle UPenn and TUSZ datasets range from 16 to 76 channels and 23 to 31 channels, respectively.
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• Lastly, there are huge variations across several characteristics that prevent studies from truly testing their trained algorithm on another dataset without re‐tuning the algorithm.
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Every time you will open the app you will also need to log in to your account. The next step will be to create an account in the Aviator Hack Predictor application. Actually, you will not need to enter a lot of personal information and it will take only a few minutes. It is also a very simple process and after that, you will be able to use all the functions of the Predictor application. But there is also the Aviator Predictor Hack application for PC and laptops. And it means that you will be able to use the app on your desktop device.

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• Long‐term EEG continuous datasets consist of more than 24 hours of continuous recording with small time discontinuities in some cases, whereas short‐term EEG datasets contain recordings of less than 24 hours.
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• In this narrative review, we compiled and compared the different characteristics of the publicly available EEG datasets that are commonly used to develop seizure detection and prediction algorithms.
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First, we searched for studies that used EEG signals for seizure detection or prediction on Scopus and Web of Science (WOS), allowing us to include studies from different fields such as medical, information technology, and engineering. In terms of discriminating patients with complete and incomplete recovery, the three best individually performing biomarkers in outcome prediction were Aβ40, NF-L, and Aβ42 (Table 4). Threshold indicates a value or level that needs to be exceeded to detect unfavorable outcome. Because Pinup Aviator is built using random number generators, there is sadly no perfect aviator game prediction tool or 100% aviator game strategy or tools to help players win.

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In other words, when using only the HCTS, 11 patients out of the 49 with favorable outcomes were correctly detected, and when using the HCTS together with biomarkers, 29 patients with favorable outcomes were correctly detected. When studied alone, the HCTS had the highest pAUCs of the tested covariates, followed by Aβ40 and Aβ42. The individual specificities of the HCTS and biomarkers remained low (2–33%) in isolation, but the optimal combination panel yielded a specificity of 59% when the sensitivity was set above 90%. The main task of the study, i.e., whether it is a seizure detection or prediction task, will affect the choice of the dataset. Noncontinuous datasets such as the University of Bonn and Kaggle UPenn datasets only include ictal segments without preictal segments, so they should only be used for seizure detection classification. Similarly, noncontinuous datasets, such as the remaining Kaggle datasets that include only preictal and interictal segments should only be used for seizure prediction classification.

• Both Gradisek and Vos have reported that GFAP and S100B improve the performance of clinical parameters in outcome prediction (61, 62).
• CT, computerized tomography; TBI, traumatic brain injury; tSAH, traumatic subarachnoid hemorrhage.
• This applied concentration did not affect the statistics results.

32 , 33

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Table 5b

Most modern TBI biomarker studies have investigated the individual prediction abilities of different molecules. The studies show that single biomarkers tend to have low specificities when sensitivity is set above 90%. Therefore, individual blood-based biomarkers may not be applicable for clinical practice as stand-alone tools (19, 28, 31), which is expected due to the complexity of TBI. Combining several biomarkers or combining biomarkers with clinical characteristics have been suggested to improve diagnostic and predictive abilities (31, 32). Thus, biomarkers may provide additional value in outcome prediction of TBI when used in combination with predictive neuroimaging scores. However, studies on blood-based biomarkers complementing head imaging scores are scarce.

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52 In our study, the effect of this bias is minimal, as we were only interested in how many of the studies use the data rather than the results themselves. Based on Table 8, the number of seizure events is largely affected by the total size of the dataset (Total recorded segments x recordings length per segment).

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Several brain-enriched protein biomarkers have been studied in combination and isolation as tools for predicting TBIs of different severities (16–18). Biomarkers may offer incremental value in outcome prediction when used in combination with neuroimaging scores. We found that panels of biomarkers significantly outperformed individual biomarkers in this setting (19). The Pin Up Aviator app is not just about accessibility; it’s also about delivering an exceptional user experience.

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• Do not try to use the Pin-Up Casino Aviator hack, otherwise, you risk losing your account and all funds on your balance.
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• Scalp EEG recording is easy to acquire in clinical settings and is relatively cheap compared with intracranial EEG.
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• There were patients with missing data on pupil reactivity, events of hypoxia, hypotension, and hypoglycemia, and these were excluded from the comparative analysis.
• It has been shown that seizure likelihood also increases if a seizure occurred recently and in certain groups of patients, cyclic trends such as the timing of the day can also be found in periods leading to seizures.
• As discussed earlier, iEEG signals have a higher signal‐to‐noise ratio compared with surface EEG as they are less affected by artifacts and environmental factors.
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